Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HTR7 | P34969 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3703420 | 0.99 | C5AR1 (0.60) | C5AR1KDM4EALDH1A1KMT2AHTR7 | |
| SCHEMBL3710001 | 0.88 | KDM4E (0.62) | KDM4EALDH1A1KMT2AHTR7MEN1 | |
| Hydrochloric Acid SCHEMBL3708648 | 0.85 | C5AR1 (0.58) | C5AR1KDM4EALDH1A1HTR7TDP1 | |
| SCHEMBL3706431 | 0.84 | GLA (0.62) | C5AR1KDM4EALDH1A1KMT2A | |
| SCHEMBL3705468 | 0.84 | KDM4E (0.57) | C5AR1KDM4EALDH1A1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL3704470 | 0.84 | KDM4E (0.56) | C5AR1KDM4EALDH1A1KMT2ATDP1 | |
| SCHEMBL3705960 | 0.84 | HTR7 (0.65) | KDM4EALDH1A1KMT2AHTR7MEN1 | |
| SCHEMBL3563737 | 0.81 | KDM4E (0.64) | KDM4EALDH1A1KMT2AHTR7MEN1 | |
| SCHEMBL3704635 | 0.81 | ALDH1A1 (0.64) | C5AR1KDM4EALDH1A1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL3710903 | 0.80 | KDM4E (0.62) | KDM4EALDH1A1KMT2AHTR7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | claimed |
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |