Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 13/20 | 0.43 |
| ▸ | THRA | P10827 | 12/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708122 | 0.86 | THRB (0.45) | THRBTHRA | |
| SCHEMBL3708160 | 0.84 | THRA (0.61) | THRBTHRA | |
| SCHEMBL3704624 | 0.82 | THRB (0.48) | THRBTHRA | |
| SCHEMBL3712191 | 0.82 | THRA (0.51) | THRBTHRA | |
| SCHEMBL3708478 | 0.82 | THRB (0.42) | THRBTHRA | |
| SCHEMBL3709651 | 0.82 | THRB (0.52) | THRBTHRA | |
| SCHEMBL3706492 | 0.82 | THRB (0.40) | THRBTHRA | |
| SCHEMBL3712021 | 0.80 | THRB (0.42) | THRBTHRA | |
| SCHEMBL3706100 | 0.80 | THRB (0.45) | THRBTHRA | |
| SCHEMBL3703818 | 0.79 | THRB (0.47) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | claimed |
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | disclosed |