Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3704724 | 0.85 | GAA (0.30) | NMT1 | |
| SCHEMBL3704722 | 0.85 | HTR2C (0.31) | NMT1 | |
| SCHEMBL4137780 | 0.84 | NMT1 (0.36) | NMT1 | |
| SCHEMBL3654646 | 0.80 | ABCC9 (0.34) | — | |
| Carbamic Acid SCHEMBL3651236 | 0.77 | CA2 (0.35) | — | |
| SCHEMBL4131329 | 0.77 | HTR2C (0.35) | NMT1 | |
| SCHEMBL4126794 | 0.74 | CA12 (0.39) | — | |
| Hydrochloric Acid SCHEMBL4132114 | 0.69 | CACNA2D1 (0.36) | NMT1 | |
| SCHEMBL4129164 | 0.66 | HTR6 (0.38) | — | |
| Carbamic Acid SCHEMBL3651234 | 0.64 | HTR2C (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009041705-A9 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009041705-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-02 | — | — | WO | disclosed |