Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1449814 | 0.80 | DGAT1 (0.34) | — | |
| SCHEMBL1450232 | 0.78 | HTR2A (0.33) | — | |
| SCHEMBL1449700 | 0.76 | PIK3R1 (0.41) | — | |
| SCHEMBL1449637 | 0.73 | HTR2A (0.38) | — | |
| SCHEMBL3692573 | 0.72 | VNN1 (0.33) | — | |
| SCHEMBL1450149 | 0.71 | GPR119 (0.44) | — | |
| SCHEMBL11901108 | 0.70 | GPR119 (0.39) | — | |
| SCHEMBL4572398 | 0.70 | PIK3R1 (0.38) | — | |
| SCHEMBL20568753 | 0.69 | NOTUM (0.38) | — | |
| SCHEMBL1449824 | 0.63 | RET (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144902-B1 | [6,6]AND [6,7]-BICYCLIC GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2012-05-16 | — | — | EP | disclosed |