⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27754324 | 0.85 | ALDH1A1 (0.44) | — | |
| SCHEMBL5755301 | 0.81 | — | — | |
| SCHEMBL2585956 | 0.79 | CALM1 (0.43) | — | |
| SCHEMBL28229966 | 0.78 | TDP1 (0.38) | — | |
| SCHEMBL597661 | 0.77 | — | — | |
| SCHEMBL58507 | 0.75 | — | — | |
| SCHEMBL232800 | 0.75 | — | — | |
| SCHEMBL191768 | 0.75 | — | — | |
| SCHEMBL2542283 | 0.75 | — | — | |
| SCHEMBL232726 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920208-A | Boric acid-containing indole aryl sulfone derivative and preparation method and application thereof | 山东大学 | 2021-06-08 | — | — | CN | claimed |
| CN-109912782-A | The conjugated polymer and the preparation method and application thereof of phenyl boric acid modification | 中国科学院化学研究所 | 2019-06-21 | — | — | CN | claimed |
| CN-105367568-A | Riociguat preparation method | ZHEJIANG JINGXIN PHARMACEUTICAL CO LTD | 2016-03-02 | — | — | CN | claimed |
| US-9139546-B2 | Tri-aryl/heteroaromatic cannabinoids and use thereof | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2015-09-22 | — | — | US | claimed |
| CN-103275146-B | A kind of Gastrodine chemical synthesis process being suitable for industrialization | QINGDAO AGRICULTURAL UNIVERSITY (CN) | 2015-07-29 | — | — | CN | claimed |
| CN-102603630-A | O-aminobenzoic acid sulfonylation derivative as well as preparation method and application thereof | UNIV BEIJING SCIENCE & TECH | 2012-07-25 | — | — | CN | claimed |
| US-20110207748-A1 | Tri-Aryl/Heteroaromatic Cannabinoids and Use Thereof | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-08-25 | — | — | US | claimed |
| CN-102060798-A | Method for synthesizing 2-(1-hydro-4-tetrazole)-4'-methylbiphenyl and derivatives thereof | UNIV FUDAN | 2011-05-18 | — | — | CN | claimed |
| US-7888365-B2 | Tri-aryl/heteroaromatic cannabinoids and use thereof | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2011-02-15 | — | — | US | claimed |
| EP-2131655-A2 | TRI-ARYL/HETEROAROMATIC CANNABINOIDS AND USE THEREOF | The University of Tennessee Research Foundation (US) | 2009-12-16 | — | — | EP | claimed |
| US-20040157966-A1 | Substituted 5-aryl-2-(2-hydroxyphenyl)-2h-benzotriazole UV absorbers, compositions stabilized therewith and process for preparation thereof | PASTOR STEPHEN D (US) | 2004-08-12 | — | — | US | claimed |
| US-20040092628-A1 | Substituted 5-aryl-2-(2-hydroxyphenyl)-2h-benzotriazole UV absorbers, compositions stabilized therewith and process for preparatiion thereof | PASTOR STEPHEN D (US) | 2004-05-13 | — | — | US | claimed |
| US-20030213164-A1 | Substituted 5-aryl-2-(2-hydroxyphenyl)-2H-benzotriazole UV absorbers, compositions stabilized therewith and process for preparation thereof | PASTOR STEPHEN D (US) | 2003-11-20 | — | — | US | claimed |
| US-6649770-B1 | Exhibit superior hydrolytic stability, handling and storage stability as well as good resistance to extractability when present in stabilized composition | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-11-18 | — | — | US | claimed |
| EP-1353673-A1 | CAMPTOTHECIN DERIVATIVES | California Pacific Medical Center (US) | 2003-10-22 | — | — | EP | claimed |
| EP-1337520-A1 | SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS | Ciba SC Holding AG (CH) | 2003-08-27 | — | — | EP | claimed |
| WO-2002056885-A1 | CAMPTOTHECIN DERIVATIVES | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2002-07-25 | — | — | WO | claimed |
| WO-2002042281-A1 | SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-05-30 | — | — | WO | claimed |
| US-6350756-B1 | USEFUL FOR TREATING CANCER; (20S) ESTERS WITH AN OXYALKANOIC ACID; | CALIFORNIA PACIFIC MEDICAL CENTER | 2002-02-26 | — | — | US | claimed |
| EP-0889020-B1 | A process for the production of benzene derivatives | KOLON INC (KR) | 2001-11-14 | — | — | EP | claimed |