⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28229966 | 0.87 | TDP1 (0.38) | — | |
| SCHEMBL9579530 | 0.84 | TDP1 (0.35) | — | |
| SCHEMBL370560 | 0.81 | — | — | |
| SCHEMBL159206 | 0.79 | MAOA (0.44) | — | |
| SCHEMBL9788933 | 0.77 | — | — | |
| SCHEMBL1167334 | 0.77 | — | — | |
| SCHEMBL3169832 | 0.77 | — | — | |
| SCHEMBL1244469 | 0.77 | — | — | |
| SCHEMBL1244286 | 0.77 | — | — | |
| SCHEMBL6938669 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2865669-B1 | NOVEL REBAMIPIDE PRODRUG, METHOD FOR PRODUCING SAME, AND USAGE THEREOF | SAMJIN PHARM CO LTD (KR) | 2021-04-28 | — | — | EP | disclosed |
| CN-105658628-A | Novel arylalkene derivatives and use thereof as selective estrogen receptor modulators | 北京赛林泰医药技术有限公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-103228622-B | The agonist of GPR40 | CONNEXIOS LIFE SCIENCES Pvt.,Ltd. (IN) | 2016-01-20 | — | — | CN | disclosed |
| CN-102459258-B | Preparation and use of 1,2, 4-triazolo [1,5a ] pyridine derivatives | CEPHALON, INC. (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-102480956-B | Pyrido [4,3-b] indoles and methods of use | MEDIVATION TECHNOLOGIES INC | 2015-04-08 | — | — | CN | disclosed |
| CN-104130247-A | Human T2R bitter taste receptors and the use thereof | SENOMYX INC | 2014-11-05 | — | — | CN | disclosed |
| CN-102712577-B | Substituted 3-phenylpropionic acids and the use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-15 | — | — | CN | disclosed |
| CN-102753558-B | Nitroimidazooxazines and their use in antitubercular therapy | GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT (US) | 2014-10-15 | — | — | CN | disclosed |
| CN-101998959-B | Benzoxazole carboxamide inhibitors of poly(ADP-ribose)polymerase (PARP) | BIOMARIN PHARM INC | 2013-08-28 | — | — | CN | disclosed |
| CN-103228622-A | Agonists of gpr40 | CONNEXIOS LIFE SCIENCES PVT LTD | 2013-07-31 | — | — | CN | disclosed |
| CN-1918165-A | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL MYERS SQUIBB CO (US) | 2007-02-21 | — | — | CN | disclosed |
| CN-1809536-A | Inhibitors of Akt activity | MERCK & CO INC (US) | 2006-07-26 | — | — | CN | disclosed |
| EP-1165085-B1 | PHTHALAZINE DERIVATIVES FOR TREATING INFLAMMATORY DISEASES | NOVARTIS AG (CH) | 2006-06-14 | — | — | EP | disclosed |
| CN-1039324-C | Substituted azacyclo-pyrimidine compounds, their pharmaceutical salts or N-oxides, and their use as anti-inflammatory agents | AMERICAN HOME PROD (US) | 1998-07-29 | — | — | CN | disclosed |
| CN-1182423-A | Fungicidal cyclic amides | DU PONT (US) | 1998-05-20 | — | — | CN | disclosed |
| US-5656633-A | Carbostyril derivatives and pharmaceutical compositions containing the same for use as a disturbance-of-consciousness improving agent, central nervous system stimulant or sigma receptor agonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| US-5556857-A | SIGMA RECEPTOR AGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0512525-B1 | Carbostyril derivatives and pharmaceutical compositions containing the same for use as a disturbance-of-consciousness improving agent, central nervous system stimulant or sigma receptor agonist | OTSUKA PHARMA CO LTD (JP) | 1994-11-30 | — | — | EP | disclosed |
| CN-1072682-A | SUBSTITUTED PYRIMIDINES | AMERICAN HOME PROD (US) | 1993-06-02 | — | — | CN | disclosed |
| EP-0512525-A1 | Carbostyril derivatives and pharmaceutical compositions containing the same for use as a disturbance-of-consciousness improving agent, central nervous system stimulant or sigma receptor agonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |