Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 9/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3706391 | 0.88 | HIF1A (0.49) | HIF1AHSP90AA1KDM4ECA12CA1 | |
| SCHEMBL3705603 | 0.88 | HSP90AA1 (0.48) | HIF1AHSP90AA1NFKB1NFKB2RELA | |
| SCHEMBL31376243 | 0.86 | HSP90AA1 (0.51) | HIF1AHSP90AA1NFKB1NFKB2RELA | |
| SCHEMBL30040796 | 0.77 | HSP90AA1 (0.50) | HIF1AHSP90AA1NFKB1NFKB2RELA | |
| SCHEMBL16244979 | 0.77 | HSP90AA1 (0.50) | HIF1AHSP90AA1NFKB1NFKB2RELA | |
| SCHEMBL30576685 | 0.76 | DYRK3 (0.48) | HIF1AHSP90AA1KDM4ECA12CA1 | |
| SCHEMBL29073790 | 0.76 | DYRK3 (0.48) | HIF1AHSP90AA1KDM4ECA12CA1 | |
| Praecansone B SCHEMBL31237500 | 0.76 | NFKB1 (0.51) | HIF1AHSP90AA1NFKB1NFKB2RELA | |
| SCHEMBL31376180 | 0.76 | NFKB1 (0.68) | HIF1ANFKB1NFKB2RELAKDM4E | |
| SCHEMBL31376248 | 0.75 | NFKB1 (0.70) | HIF1ANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190187-A1 | FORMULATION FOR ENHANCED DELIVERY OF PHENETHYLAMINE | KNELLER BRUCE W | 2007-08-16 | — | — | US | claimed |
| WO-2010092162-A1 | NEUROACTIVE PLANT EXTRACT FROM HYPERICUM POLYANTHEMUM | UNIVERSITE DE ROUEN (FR) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010092162-A1 | NEUROACTIVE PLANT EXTRACT FROM HYPERICUM POLYANTHEMUM | UNIVERSITE DE ROUEN (FR) | 2010-08-19 | — | — | WO | disclosed |
| US-20070190187-A1 | FORMULATION FOR ENHANCED DELIVERY OF PHENETHYLAMINE | KNELLER BRUCE W | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070190187-A1 | FORMULATION FOR ENHANCED DELIVERY OF PHENETHYLAMINE | MAOB, PNMT, MAOA | HIF1A 1609/4885HSP90AA1 3852/4885NFKB1 2583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.