Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 4/20 | 0.37 |
| ▸ | CD44 | P16070 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37705 | 0.76 | PNMT (0.39) | PNMTCD44MAOBALOX15HSD17B10 | |
| SCHEMBL29374426 | 0.74 | PNMT (0.50) | PNMTCD44MAOBALOX15HSD17B10 | |
| SCHEMBL214465 | 0.74 | PNMT (0.50) | PNMTCD44MAOBALOX15HSD17B10 | |
| SCHEMBL209284 | 0.68 | NPC1 (0.34) | ALOX15HSD17B10HTR2C | |
| SCHEMBL300921 | 0.68 | PNMT (0.32) | PNMTCD44MAOBALOX15HSD17B10 | |
| SCHEMBL10973923 | 0.64 | NOS3 (0.31) | — | |
| SCHEMBL10320905 | 0.64 | HTR2C (0.52) | PNMTCD44MAOBPRCPHTR2C | |
| SCHEMBL20477699 | 0.63 | TSHR (0.42) | PNMTCD44MAOBHTR2C | |
| SCHEMBL157430 | 0.63 | — | — | |
| SCHEMBL1623564 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212282-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-08-04 | — | — | EP | claimed |
| WO-2009052065-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-04-23 | — | — | WO | claimed |