SCHEMBL214465

SCHEMBL214465

c1ccc2c(c1)CNNC2

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PNMT P11086 3/20 0.50
CD44 P16070 1/20 0.50
MAOB P27338 1/20 0.50
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46
HTR2C P28335 1/20 0.43
TSHR P16473 1/20 0.42
PRCP P42785 1/20 0.41
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29374426 1.00 PNMT (0.50) PNMTCD44MAOBALOX15HSD17B10
SCHEMBL4505791 0.84 PNMT (0.62) PNMTCD44MAOBALOX15HSD17B10
SCHEMBL10612 0.79
SCHEMBL29351494 0.79
SCHEMBL13590042 0.79 PNMT (0.65) PNMTCD44MAOBALOX15HSD17B10
Hydrochloric Acid SCHEMBL4702076 0.76 PNMT (0.62) PNMTCD44MAOBALOX15HSD17B10
Hydrochloric Acid SCHEMBL29371527 0.76 PNMT (0.62) PNMTCD44MAOBALOX15HSD17B10
Ammonia Solution, Strong SCHEMBL16296133 0.76 PNMT (0.62) PNMTCD44MAOBALOX15HSD17B10
SCHEMBL28633341 0.76 PNMT (0.62) PNMTCD44MAOBALOX15HSD17B10
Methane SCHEMBL11147358 0.76 PNMT (0.62) PNMTCD44MAOBALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1427 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116422109-A Self-extraction layered carbon dioxide trapping system and method 嘉兴市碳捕手科技有限责任公司 2023-07-14 CN claimed
US-20230132356-A2 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-04-27 US claimed
CN-113861128-A Polymerizable compound and optically anisotropic body 江苏创拓新材料有限公司 2021-12-31 CN claimed
EP-2602242-A1 PROCESS FOR PREPARING COMPOUND BY NOVEL SANDMEYER-LIKE REACTION USING NITROXIDE RADICAL COMPOUND AS REACTION CATALYST DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-06-12 EP claimed
US-20130144061-A1 PROCESS FOR PREPARING A COMPOUND BY A NOVEL SANDMEYER-LIKE REACTION USING A NITROXIDE RADICAL COMPOUND AS A REACTION CATALYST DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-06-06 US claimed
EP-1852420-B1 Indole compounds for treating respiratory disorders ONO PHARMACEUTICAL CO (JP) 2012-10-17 EP claimed
US-8153625-B2 Nitrogen-containing heterocyclic compounds and medicinal use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2012-04-10 US claimed
US-7759336-B2 Nitrogen-containing heterocyclic compounds and medicinal use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2010-07-20 US claimed
US-7402580-B2 Fused pyridazine derivative compounds and drugs containing these compounds as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2008-07-22 US claimed
EP-1058681-B1 NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME SEOUL PHARM CO LTD (KR) 2003-05-07 EP claimed
EP-1058681-A1 NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME Seoul Pharm. Co., Ltd. (KR) 2000-12-13 EP claimed
US-5942511-A PROTECTION OF HUMAN TISSUE FROM RADIATION Kwon, Soon Kyoung (KR) 1999-08-24 US claimed
WO-1999036407-A1 NOVEL ALLYLTHIOPYRIDAZINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME SEOUL PHARM. CO., LTD. (KR) 1999-07-22 WO claimed
JP-1207279-A None JP disclosed
US-20260146047-A1 MACROCYCLIC HETEROCYCLE COMPOUNDS AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-05-28 US disclosed
US-12637418-B2 Heterocyclic compounds as antagonist of NMDA TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-05-26 US disclosed
US-4992434-A Prevention of infestation of plants by phytopathogenic microorganisms CIBA-GEIGY CORPORATION (US) 1991-02-12 US disclosed
EP-0335831-A1 Thiazole-5-carboxylic acid amides for protecting cultivated plants against the phytotoxic activity of highly active herbicides CIBA-GEIGY AG (CH) 1989-10-04 EP disclosed
JP-H01207279-A PRODUCTION OF PHTHALAZINE MITSUBISHI KASEI CORP 1989-08-21 JP disclosed
US-4659711-A 1,2,3,4-Tetrahydrophthalazine and hexahydropyridazine compounds for treating hypertension USV PHARMACEUTICAL CORPORATION (US) 1987-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130144061-A1 PROCESS FOR PREPARING A COMPOUND BY A NOVEL SANDMEYER-LIKE REACTION USING A NITROXIDE RADICAL COMPOUND AS A REACTION CATALYST TYR, NOX5, NOXO1 PNMT 76/4885CD44 1585/4885MAOB 995/4885
US-20230132356-A2 ORGANIC LIGHT-EMITTING DEVICE L1CAM, CRY1, LAGE3 PNMT 432/4885CD44 2861/4885MAOB 884/4885
US-12637418-B2 Heterocyclic compounds as antagonist of NMDA GRIN1, GRIN3A, GRIN2A PNMT 2303/4885CD44 3164/4885MAOB 1348/4885
US-20260146047-A1 MACROCYCLIC HETEROCYCLE COMPOUNDS AND USE THEREOF HCRTR2, HCRTR1, NPY1R PNMT 1603/4885CD44 4426/4885MAOB 578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.