Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2337987 | 0.93 | LPAR1 (0.40) | LPAR1P2RX7LPAR2LPAR3SLC26A6 | |
| SCHEMBL3702504 | 0.93 | ALDH1A1 (0.37) | ALDH1A1MAOBHDAC4HDAC6HTT | |
| SCHEMBL2334207 | 0.91 | ALDH1A1 (0.42) | ALDH1A1HDAC4HDAC6HTTALOX15 | |
| SCHEMBL2340991 | 0.90 | KLK7 (0.38) | ALDH1A1ALOX15SMN1; SMN2BACE1MEN1 | |
| SCHEMBL2335475 | 0.89 | KDM4E (0.39) | ALDH1A1HDAC4HDAC6HTTSYK | |
| SCHEMBL3705660 | 0.86 | SYK (0.35) | ALDH1A1HDAC4HDAC6HTTSYK | |
| SCHEMBL2341313 | 0.85 | LPAR1 (0.40) | ALDH1A1LPAR1LPAR2LPAR3SLC26A6 | |
| SCHEMBL3715778 | 0.85 | KDM4E (0.38) | ALDH1A1HDAC4HDAC6HTTL3MBTL1 | |
| SCHEMBL3706822 | 0.85 | ALDH1A1 (0.37) | ALDH1A1HDAC4HDAC6HTTSYK | |
| SCHEMBL3702204 | 0.84 | TP53 (0.38) | ALDH1A1MAOBHDAC4HDAC6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |