SCHEMBL3706464

SCHEMBL3706464

CC(C)NC(=O)N(CC(=O)O)c1cc(Cl)c(Oc2ccc(O)c(C(C)C)c2)c(Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRA P10827 13/20 0.61
THRB P10828 13/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3702776 0.87 THRB (0.58) THRATHRB
SCHEMBL3704572 0.86 THRB (0.54) THRATHRB
SCHEMBL3706172 0.85 THRB (0.58) THRATHRB
SCHEMBL3223233 0.84 THRA (0.69) THRATHRB
SCHEMBL3221807 0.84 THRA (0.61) THRATHRB
SCHEMBL3708498 0.84 THRA (0.61) THRATHRB
SCHEMBL3805350 0.83 THRB (0.58) THRATHRB
SCHEMBL3702938 0.83 THRA (0.60) THRATHRB
SCHEMBL3226690 0.83 THRA (0.60) THRATHRB
SCHEMBL3711950 0.82 THRA (0.59) THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010086878-A2 THYROID RECEPTOR MODULATORS CADILA HEALTHCARE LIMITED (IN) 2010-08-05 WO claimed
WO-2010086878-A2 THYROID RECEPTOR MODULATORS CADILA HEALTHCARE LIMITED (IN) 2010-08-05 WO disclosed