Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621039 | 0.79 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CCYSLTR2CYSLTR1 | |
| SCHEMBL4843352 | 0.79 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CCYSLTR2CYSLTR1 | |
| SCHEMBL18377997 | 0.77 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CCYSLTR2CYSLTR1 | |
| SCHEMBL11200726 | 0.76 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CCYSLTR2CYSLTR1 | |
| SCHEMBL7643940 | 0.76 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CCYSLTR2CYSLTR1 | |
| SCHEMBL19254463 | 0.76 | TSHR (0.55) | ADRA2AADRA2BADRA2CCYSLTR2CYSLTR1 | |
| SCHEMBL872725 | 0.76 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CCYSLTR2CYSLTR1 | |
| SCHEMBL903364 | 0.74 | CYSLTR2 (0.42) | ADRA2AADRA2BADRA2CCYSLTR2CYSLTR1 | |
| SCHEMBL10439471 | 0.74 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CCYSLTR2CYSLTR1 | |
| SCHEMBL14840158 | 0.74 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CCYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428512-A2 | Fluorene compound, light-emitting element, light-emitting device, electronic device and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-03-14 | — | — | EP | disclosed |