SCHEMBL3706716

SCHEMBL3706716

O=C(Cl)OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.34
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13894748 0.84 THRB (0.37) THRBCA1CA2
SCHEMBL22801425 0.84 THRB (0.37) THRBCA1CA2
SCHEMBL22801426 0.82 THRB (0.40) THRBCA1CA2
SCHEMBL30360199 0.82 THRB (0.31) THRB
SCHEMBL12199963 0.82 THRB (0.31) THRB
SCHEMBL2568582 0.82 THRB (0.31) THRB
SCHEMBL717931 0.82 THRB (0.33) THRB
SCHEMBL14456628 0.81 CA1 (0.34) THRBCA1CA2
SCHEMBL9765338 0.81 CA1 (0.34) THRBCA1CA2
SCHEMBL14456629 0.81 CA1 (0.34) THRBCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8242312-B2 Urethane and urea fluorosurfactants E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-08-14 US disclosed
US-20120122999-A1 URETHANE AND UREA FLUOROSURFACTANTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-05-17 US disclosed
US-6479690-B1 Phosgenation under pressure of alcohol's for producing chloroformates SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 2002-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120122999-A1 URETHANE AND UREA FLUOROSURFACTANTS QSOX1, SRM, AFF1 THRB 3588/4885CA1 2586/4885CA2 3607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.