SCHEMBL3706871

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3698928	0.93	APAF1 (0.45)	HDAC8GOT1APAF1CASP3CASP9
	SCHEMBL3700734	0.93	HDAC8 (0.46)	HDAC8GOT1APAF1CASP3CASP9
	SCHEMBL3698678	0.93	BCHE (0.46)	HDAC8GOT1APAF1CASP3CASP9
	SCHEMBL3693007	0.90	APAF1 (0.53)	HDAC8GOT1APAF1CASP3CASP9
	SCHEMBL5955979	0.88	BCHE (0.49)	BCHEACHEMEN1KMT2ARAB9A
	SCHEMBL3698791	0.85	APAF1 (0.49)	HDAC8APAF1CASP3CASP9CYCS
	SCHEMBL5956385	0.84	APAF1 (0.52)	HDAC8APAF1CASP3CASP9CYCS
	SCHEMBL29411284	0.83	ACHE (0.44)	BCHEACHEALDH1A1
	SCHEMBL5956062	0.83	ACHE (0.44)	BCHEACHEALDH1A1
	SCHEMBL3775357	0.83	APAF1 (0.72)	HDAC8APAF1CASP3CASP9CYCS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.