Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 6/20 | 1.00 |
| ▸ | PRKCG | P05129 | 5/20 | 1.00 |
| ▸ | PRKCB | P05771 | 5/20 | 1.00 |
| ▸ | PRKCH | P24723 | 5/20 | 1.00 |
| ▸ | PRKCE | Q02156 | 5/20 | 1.00 |
| ▸ | PRKCQ | Q04759 | 5/20 | 1.00 |
| ▸ | PRKCD | Q05655 | 5/20 | 1.00 |
| ▸ | PRKD3 | O94806 | 4/20 | 1.00 |
| ▸ | PRKCI | P41743 | 4/20 | 1.00 |
| ▸ | PRKCZ | Q05513 | 4/20 | 1.00 |
| ▸ | PRKD1 | Q15139 | 4/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phorbol Myristate Acetate SCHEMBL22722418 | 1.00 | PRKCA (1.00) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| Phorbol Myristate Acetate SCHEMBL17368149 | 1.00 | PRKCA (1.00) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| Phorbol Myristate Acetate SCHEMBL18550994 | 1.00 | PRKCA (1.00) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| Phorbol Myristate Acetate SCHEMBL22736719 | 1.00 | PRKCA (1.00) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| Phorbol Myristate Acetate SCHEMBL21165759 | 1.00 | PRKCA (1.00) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL16174732 | 1.00 | PRKCA (1.00) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| Phorbol Myristate Acetate SCHEMBL15423125 | 1.00 | PRKCA (1.00) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| Phorbol Myristate Acetate SCHEMBL19271683 | 1.00 | PRKCA (1.00) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| Phorbol Myristate Acetate SCHEMBL115567 | 1.00 | PRKCA (1.00) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| Phorbol Myristate Acetate SCHEMBL6993831 | 1.00 | PRKCA (1.00) | PRKCAPRKCGPRKCBPRKCHPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180171290-A1 | METHOD OF PRODUCING PROGENITOR CELLS FROM DIFFERENTIATED CELLS | REGENERTECH PTY LIMITED (AU) | 2018-06-21 | — | — | US | disclosed |
| EP-2792666-B1 | PHORBOL TYPE DITERPENE COMPOUND, PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF VIRAL INFECTIOUS DISEASES INCLUDING SAME | KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY (KR) | 2018-04-25 | — | — | EP | disclosed |
| US-9174925-B2 | Phorbol type diterpene compound, pharmaceutical composition for treatment or prevention of viral infectious diseases including same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2015-11-03 | — | — | US | disclosed |
| US-20140364492-A1 | PHORBOL TYPE DITERPENE COMPOUND, PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF VIRAL INFECTIOUS DISEASES INCLUDING SAME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2014-12-11 | — | — | US | disclosed |
| EP-2792666-A2 | PHORBOL TYPE DITERPENE COMPOUND, PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF VIRAL INFECTIOUS DISEASES INCLUDING SAME | Korea Research Institute of Bioscience and Biotechnology (KR) | 2014-10-22 | — | — | EP | disclosed |
| US-20120121546-A1 | Method of Producing Progenitor Cells from Differentiated Cells | BHASIN VISHAL (NZ) | 2012-05-17 | — | — | US | disclosed |
| US-6268395-B1 | FOR EXAMPLE ANTI-HIV AGENT; HAVING HIGHER ANTIVIRAL EFFECTS AND LESS DELETERIOUS SIDE EFFECTS AS COMPARED WITH CONVENTIONALLY KNOWN ANTIVIRAL AGENTS. | LEAD CHEMICAL CO., LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120121546-A1 | Method of Producing Progenitor Cells from Differentiated Cells | ALPG, MYADM, KIT | PRKCA 1370/4885PRKCG 1091/4885PRKCB 1378/4885 |
| US-20140364492-A1 | PHORBOL TYPE DITERPENE COMPOUND, PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF VIRAL INFECTIOUS DISEASES INCLUDING SAME | IRF3, IFNG, IRF2BP2 | PRKCA 11/4885PRKCG 9/4885PRKCB 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.