SCHEMBL3707141

SCHEMBL3707141

SC1=Nc2ccccc2CO1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39
NOS2 P35228 1/20 0.39
NPC1 O15118 4/20 0.39
ALDH1A1 P00352 4/20 0.39
RAB9A P51151 4/20 0.39
MAPT P10636 3/20 0.39
LMNA P02545 3/20 0.39
KDM4E B2RXH2 2/20 0.39
GAA P10253 2/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
SIGMAR1 Q99720 1/20 0.34
ACHE P22303 6/20 0.33
KMT2A Q03164 4/20 0.33
BCHE P06276 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALOX12 P18054 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28774790 0.75 NOS3 (0.39) NOS3NOS1NOS2NPC1ALDH1A1
SCHEMBL10591420 0.75 NOS3 (0.39) NOS3NOS1NOS2NPC1ALDH1A1
SCHEMBL1651152 0.75 NOS3 (0.48) NOS3NOS1NOS2NPC1ALDH1A1
SCHEMBL30129926 0.73 NPC1 (0.42) NOS3NOS1NOS2NPC1ALDH1A1
SCHEMBL11907198 0.73 NPC1 (0.42) NOS3NOS1NOS2NPC1ALDH1A1
SCHEMBL10654837 0.72 NPC1 (0.49) NOS3NOS1NOS2NPC1ALDH1A1
SCHEMBL28842368 0.71 NOS3 (0.36) NOS3NOS1NOS2NPC1ALDH1A1
SCHEMBL13700959 0.70 MAPT (0.43) NOS3NOS1NOS2NPC1ALDH1A1
SCHEMBL18100313 0.69 NPC1 (0.42) NOS3NOS1NOS2NPC1ALDH1A1
SCHEMBL12352165 0.69 PRF1 (0.36) NOS3NOS1NOS2NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2207750-A1 STABILIZATION OF HYDROXYLAMINE CONTAINING SOLUTIONS AND METHOD FOR THEIR PREPARATION EKC Technology, INC. (US) 2010-07-21 EP disclosed
WO-2009058273-A1 STABILIZATION OF HYDROXYLAMINE CONTAINING SOLUTIONS AND METHOD FOR THEIR PREPARATION EKC TECHNOLOGY, INC. (US) 2009-05-07 WO disclosed
US-20090112024-A1 STABILIZATION OF HYDROXYLAMINE CONTAINING SOLUTIONS AND METHOD FOR THEIR PREPARATION EKC TECHNOLOGY, INC. 2009-04-30 US disclosed
US-7491846-B2 Process for producing hydroxylamine SHOWA DENKO K.K. (JP) 2009-02-17 US disclosed
US-20080193362-A1 Process for Producing Hydroxylamine SHOWA DENKO K.K. (JP) 2008-08-14 US disclosed
EP-1663862-A2 PROCESS FOR PRODUCING HYDROXYLAMINE Showa Denko K.K. (JP) 2006-06-07 EP disclosed
WO-2005016817-A2 PROCESS FOR PRODUCING HYDROXYLAMINE SHOWA DENKO K. K. (JP) 2005-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090112024-A1 STABILIZATION OF HYDROXYLAMINE CONTAINING SOLUTIONS AND METHOD FOR THEIR PREPARATION HNMT, HMOX2, EGLN2 NOS3 210/4885NOS1 221/4885NOS2 90/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.