Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 11/20 | 0.50 |
| ▸ | THRB | P10828 | 9/20 | 0.50 |
| ▸ | THRA | P10827 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709214 | 0.93 | RORC (0.50) | RORCTHRBTHRA | |
| SCHEMBL3710472 | 0.90 | RORC (0.47) | RORCTHRBTHRA | |
| SCHEMBL3705671 | 0.90 | THRB (0.55) | THRBTHRA | |
| SCHEMBL3714422 | 0.85 | THRB (0.44) | THRBTHRA | |
| SCHEMBL3702743 | 0.83 | RORC (0.47) | RORCTHRBTHRA | |
| SCHEMBL3702723 | 0.83 | THRB (0.45) | RORCTHRBTHRA | |
| SCHEMBL3715134 | 0.82 | THRB (0.55) | THRBTHRA | |
| SCHEMBL5284086 | 0.80 | THRB (0.59) | RORCTHRBTHRA | |
| SCHEMBL3706521 | 0.78 | RORC (0.53) | RORCTHRBTHRA | |
| SCHEMBL3715369 | 0.77 | THRB (0.55) | RORCTHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | disclosed |