Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3395841 | 0.99 | PRMT6 (0.39) | PRMT6SERPINE1SIRT2PIM1PIM2 | |
| SCHEMBL3705545 | 0.95 | PRMT6 (0.37) | PRMT6SERPINE1PIM1PIM2TMEM97 | |
| Hydrochloric Acid SCHEMBL3394460 | 0.94 | ACHE (0.37) | PRMT6SERPINE1TMEM97SIGMAR1PTGDR2 | |
| SCHEMBL3712620 | 0.92 | SLC2A1 (0.41) | PRMT6SERPINE1PIM1PIM2SLC2A1 | |
| Hydrochloric Acid SCHEMBL3394437 | 0.91 | SLC2A1 (0.40) | PRMT6SERPINE1PIM1PIM2SLC2A1 | |
| SCHEMBL3713576 | 0.91 | SLC2A1 (0.42) | PRMT6SERPINE1PIM1PIM2SLC2A1 | |
| Hydrochloric Acid SCHEMBL3398480 | 0.90 | SLC2A1 (0.41) | PRMT6SERPINE1PIM1PIM2SLC2A1 | |
| Trifluoroacetic Acid SCHEMBL3398157 | 0.87 | SERPINE1 (0.40) | PRMT6SERPINE1SLC2A1PTGDR2 | |
| SCHEMBL3705658 | 0.84 | SLC2A1 (0.35) | PRMT6PIM1PIM2SLC2A1PTGDR2 | |
| SCHEMBL3391536 | 0.83 | PRMT6 (0.39) | PRMT6SERPINE1SLC2A1PTGDR2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081904-A1 | 4 ( 1H) -PYRIDINONE DERIVATIVES AND THEIR USE AS ANTIMALARIA AGENTS | GLAXO GROUP LIMITED (GB) | 2010-07-22 | — | — | WO | claimed |