Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT5B | Q4FZB7 | 2/20 | 0.78 |
| ▸ | KMT5C | Q86Y97 | 2/20 | 0.78 |
| ▸ | NSD2 | O96028 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | FERMT2 | Q96AC1 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | CCR1 | P32246 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4811736 | 1.00 | KMT5B (0.78) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL3706336 | 1.00 | KMT5B (0.78) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL1147527 | 1.00 | KMT5B (0.78) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6872111 | 0.93 | KMT5B (0.89) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL7207215 | 0.93 | KMT5B (0.89) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6872121 | 0.93 | KMT5B (0.89) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL7834815 | 0.92 | KMT5B (0.70) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL7834817 | 0.92 | KMT5B (0.70) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL7834821 | 0.92 | KMT5B (0.70) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL7206080 | 0.87 | KMT5B (0.79) | KMT5BKMT5CNSD2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122923-A1 | DUAL MOLECULES CONTAINING A PEROXIDE DERIVATIVE, THEIR SYNTHESIS AND THERAPEUTIC USES | SANOFI-AVENTIS (FR) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122923-A1 | DUAL MOLECULES CONTAINING A PEROXIDE DERIVATIVE, THEIR SYNTHESIS AND THERAPEUTIC USES | DUOX2, DUOX1, CYP11B2 | KMT5B 4550/4885KMT5C 4536/4885NSD2 4357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.