Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3714006 | 0.93 | LPAR1 (0.37) | TP53KMT2AMEN1KDM4ESLC26A6 | |
| SCHEMBL3715778 | 0.92 | KDM4E (0.38) | TP53L3MBTL1SMN1; SMN2NPC1PKM | |
| SCHEMBL2335475 | 0.90 | KDM4E (0.39) | TP53L3MBTL1SMN1; SMN2NPC1PKM | |
| SCHEMBL3702204 | 0.86 | TP53 (0.38) | TP53L3MBTL1SMN1; SMN2NPC1PKM | |
| SCHEMBL3705145 | 0.86 | TLR7 (0.35) | TP53SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL3703091 | 0.86 | KDM4E (0.36) | TP53L3MBTL1SMN1; SMN2NPC1PKM | |
| SCHEMBL3712524 | 0.85 | LPAR1 (0.42) | TP53PKMKDM4ESLC26A6POLB | |
| SCHEMBL3713385 | 0.84 | PLA2G10 (0.38) | TP53L3MBTL1KDM4EPOLBUSP2 | |
| SCHEMBL2341939 | 0.84 | KDM4E (0.35) | TP53L3MBTL1SMN1; SMN2NPC1PKM | |
| SCHEMBL3701871 | 0.84 | KDM4E (0.34) | TP53L3MBTL1SMN1; SMN2NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |