Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.33 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.33 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | SLC26A6 | Q9BXS9 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713385 | 0.92 | PLA2G10 (0.38) | KDM4ETP53IP6K1IP6K3IP6K2 | |
| SCHEMBL3700510 | 0.90 | LPAR1 (0.36) | TLR7KDM4EIP6K1IP6K3IP6K2 | |
| SCHEMBL3715778 | 0.89 | KDM4E (0.38) | KDM4ETP53IP6K1IP6K3IP6K2 | |
| SCHEMBL3705375 | 0.89 | TP53 (0.37) | KDM4ETP53IP6K1IP6K3IP6K2 | |
| SCHEMBL3708489 | 0.86 | TP53 (0.35) | TLR7KDM4ETP53USP2POLB | |
| SCHEMBL3712524 | 0.86 | LPAR1 (0.42) | KDM4ETP53IP6K1IP6K3IP6K2 | |
| SCHEMBL2335475 | 0.85 | KDM4E (0.39) | KDM4ETP53USP2POLBMAPT | |
| SCHEMBL3701871 | 0.83 | KDM4E (0.34) | KDM4ETP53USP2POLBMAPT | |
| SCHEMBL3714006 | 0.83 | LPAR1 (0.37) | KDM4ETP53IP6K1IP6K3IP6K2 | |
| SCHEMBL3702204 | 0.82 | TP53 (0.38) | KDM4ETP53USP2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |