Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.34 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.32 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.32 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708489 | 0.93 | TP53 (0.35) | LPAR1KDM4ETP53USP2POLB | |
| SCHEMBL3712524 | 0.92 | LPAR1 (0.42) | LPAR1KDM4ELPAR2LPAR3TP53 | |
| SCHEMBL3713385 | 0.91 | PLA2G10 (0.38) | LPAR1KDM4ELPAR2LPAR3TP53 | |
| SCHEMBL2335539 | 0.90 | LPAR1 (0.45) | LPAR1KDM4ELPAR2LPAR3TP53 | |
| SCHEMBL3709661 | 0.86 | LPAR1 (0.41) | LPAR1KDM4ELPAR2LPAR3TP53 | |
| SCHEMBL3702315 | 0.86 | LPAR1 (0.40) | LPAR1KDM4ELPAR2LPAR3TP53 | |
| SCHEMBL3715778 | 0.85 | KDM4E (0.38) | LPAR1KDM4ELPAR2LPAR3TP53 | |
| SCHEMBL3712290 | 0.85 | NR3C1 (0.38) | LPAR1KDM4ETP53PTGDR2MAPT | |
| SCHEMBL2333912 | 0.84 | DGAT1 (0.41) | LPAR1KDM4ELPAR2LPAR3TP53 | |
| SCHEMBL3706560 | 0.84 | KDM4E (0.36) | LPAR1KDM4ELPAR2LPAR3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | claimed |
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |