SCHEMBL370890

SCHEMBL370890

NC=CCc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.70
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
ARG2 P78540 1/20 0.52
IDO1 P14902 4/20 0.44
LOXL2 Q9Y4K0 2/20 0.43
TOP1 P11387 1/20 0.42
AGXT P21549 1/20 0.42
CALM1 P0DP23 1/20 0.41
CYP2A6 P11509 1/20 0.40
HTR2A P28223 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MAPK1 P28482 1/20 0.39
EPHX1 P07099 1/20 0.39
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
NOS2 P35228 1/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12655770 1.00 MAOB (0.70) MAOBCA1CA2ARG2IDO1
SCHEMBL6014431 1.00 MAOB (0.70) MAOBCA1CA2ARG2IDO1
SCHEMBL5630066 0.86 MAOB (0.52) MAOBCA1CA2ARG2IDO1
SCHEMBL5630072 0.86 MAOB (0.52) MAOBCA1CA2ARG2IDO1
SCHEMBL9285426 0.86 MAOB (0.48) MAOBCA1CA2ARG2IDO1
SCHEMBL6662237 0.83 MAOB (0.61) MAOBCA1CA2ARG2IDO1
SCHEMBL155054 0.83 MAOB (1.00) MAOBCA1CA2ARG2IDO1
SCHEMBL155055 0.83 MAOB (1.00) MAOBCA1CA2ARG2IDO1
SCHEMBL1524697 0.83 MAOB (1.00) MAOBCA1CA2ARG2IDO1
SCHEMBL9288720 0.82 MAOB (0.46) MAOBCA1CA2ARG2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 760 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113549009-B Industrial synthesis method of 2,3-dichloropyridine 河北野田农用化学有限公司 2022-07-26 CN claimed
CN-113549009-A Industrial synthesis method of 2,3-dichloropyridine 河北野田农用化学有限公司 2021-10-26 CN claimed
WO-2020029846-A1 RAPID SYNTHESIS METHOD FOR BIOMASS-BASED AMINE COMPOUND 南京农业大学 2020-02-13 WO claimed
CN-103596669-B Hydridization encapsulating material manufacturing method 韩国电气研究院 2019-04-09 CN claimed
EP-1788048-B1 HIGH-SOLID ANTICORROSIVE COATING COMPOSITION, HIGH-SOLID RAPIDLY-CURABLE ANTICORROSIVE COATING COMPOSITION, METHOD OF COATING SHIP OR THE LIKE, HIGH-SOLID ANTICORROSIVE FILM AND RAPIDLY CURED HIGH-SOLID ANTICORROSIVE FILM OBTAINED, AND COATED SHIP AND UNDERWATER STRUCTURE COATED WITH THESE COATING FILMS CHUGOKU MARINE PAINTS (JP) 2010-10-06 EP claimed
US-20090226729-A1 HIGH-SOLID ANTICORROSIVE COATING COMPOSITION, HIGH-SOLID RAPIDLY-CURABLE ANTICORROSIVE COATING COMPOSITION, METHOD OF COATING SHIP OR THE LIKE, HIGH-SOLID ANTICORROSIVE FILM AND RAPIDLY CURED HIGH- ANTICORROSIVE FILM OBTAINED, AND COATED SHIP AND UNDERWATER STRUCTURE COATED WITH THESE COATING FILMS CHUGOKU MARINE PAINTS, LTD. (JP) 2009-09-10 US claimed
US-20080234380-A1 Compositions and method for treatment of chronic inflammatory diseases SHAPIRO HOWARD K 2008-09-25 US claimed
EP-1788048-A1 HIGH-SOLID ANTICORROSIVE COATING COMPOSITION, HIGH-SOLID RAPIDLY-CURABLE ANTICORROSIVE COATING COMPOSITION, METHOD OF COATING SHIP OR THE LIKE, HIGH-SOLID ANTICORROSIVE FILM AND RAPIDLY CURED HIGH-SOLID ANTICORROSIVE FILM OBTAINED, AND COATED SHIP AND UNDERWATER STRUCTURE COATED WITH THESE COATING FILMS CHUGOKU MARINE PAINTS, LTD. (JP) 2007-05-23 EP claimed
US-20050090553-A1 Compositions and method for treatment of chronic inflammatory diseases SECANT PHARMA, LLC 2005-04-28 US claimed
US-6808933-B1 Methods of enhancing confidence in assays for analytes AGILENT TECHNOLOGIES, INC. 2004-10-26 US claimed
EP-0367484-B1 Carboxylic acid derivates GLAXO GROUP LTD (GB) 1994-02-16 EP claimed
US-5273984-A Bismuth complex having a carboxylic acid to form a salt of the basic antagonist excluding ranitidine GLAXO GROUP LIMITED (GB) 1993-12-28 US claimed
WO-1993021276-A1 MISCIBLE THERMOPLASTIC COMPOSITIONS CONTAINING POLYAMIDE/AMORPHOUS POLYAMIDE BLENDS ALLIED-SIGNAL INC. (US) 1993-10-28 WO claimed
EP-0275669-B1 USE OF HETEROCYCLIC DERIVATIVES FOR THE MANUFACTURE OF MEDICAMENTS GLAXO GROUP LIMITED (GB) 1992-09-30 EP claimed
EP-0454449-A1 Carboxylic acid derivatives GLAXO GROUP LIMITED (GB) 1991-10-30 EP claimed
EP-0367484-A1 Carboxylic acid derivates GLAXO GROUP LIMITED (GB) 1990-05-09 EP claimed
EP-0275669-A1 Use of heterocyclic derivatives for the manufacture of medicaments GLAXO GROUP LIMITED (GB) 1988-07-27 EP claimed
EP-0023578-B1 AMINOALKYLBENZENE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS SHIONOGI & CO., LTD. (JP) 1984-05-30 EP claimed
EP-0023578-A1 Aminoalkylbenzene derivatives, process for their preparation and pharmaceutical compositions SHIONOGI & CO., LTD. (JP) 1981-02-11 EP claimed
US-4220450-A Chemically induced fluorescence immunoassay SYVA COMPANY (US) 1980-09-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090553-A1 Compositions and method for treatment of chronic inflammatory diseases PCCA, HMGB1, PTGES MAOB 276/4885CA1 1403/4885CA2 1000/4885
US-20080234380-A1 Compositions and method for treatment of chronic inflammatory diseases HMGB1, PCCA, QSOX1 MAOB 262/4885CA1 1105/4885CA2 1023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.