Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.44 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.44 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.44 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.44 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709887 | 0.90 | GPR119 (0.48) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL3055131 | 0.89 | GPR119 (0.47) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL1149124 | 0.89 | CACNB4 (0.49) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL3805418 | 0.87 | KDM1A (0.53) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL3711289 | 0.87 | HRH1 (0.52) | PDE4DPDE4APDE4BPDE4CHRH1 | |
| SCHEMBL3716533 | 0.85 | CACNB4 (0.54) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL3715445 | 0.85 | HRH1 (0.48) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL3718500 | 0.85 | HRH1 (0.52) | HRH1KCNH2 | |
| SCHEMBL1149079 | 0.84 | HRH1 (0.64) | HRH1KCNH2 | |
| SCHEMBL1147914 | 0.83 | HRH1 (0.61) | HRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094643-A1 | QUINOLINE DERIVATIVES AND THEIR USES FOR RHINITIS AND URTICARIA | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |