Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 16/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 16/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718500 | 0.93 | HRH1 (0.52) | HRH1KCNH2 | |
| SCHEMBL3711289 | 0.90 | HRH1 (0.52) | HRH1KCNH2PDE4APDE4BPDE4C | |
| SCHEMBL1149079 | 0.86 | HRH1 (0.64) | HRH1KCNH2 | |
| SCHEMBL3715446 | 0.86 | HRH1 (0.47) | HRH1KCNH2 | |
| SCHEMBL1147914 | 0.86 | HRH1 (0.61) | HRH1KCNH2 | |
| SCHEMBL3040390 | 0.85 | HRH1 (0.60) | HRH1KCNH2 | |
| SCHEMBL3708948 | 0.85 | GPR119 (0.51) | HRH1KCNH2GPR119PDE4APDE4B | |
| SCHEMBL3709887 | 0.85 | GPR119 (0.48) | HRH1KCNH2GPR119PDE4APDE4B | |
| SCHEMBL3055131 | 0.84 | GPR119 (0.47) | HRH1KCNH2GPR119PDE4APDE4B | |
| SCHEMBL1149124 | 0.84 | CACNB4 (0.49) | HRH1KCNH2GPR119PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094643-A1 | QUINOLINE DERIVATIVES AND THEIR USES FOR RHINITIS AND URTICARIA | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |