SCHEMBL1149124

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12138360	0.94	PIK3CD (0.47)	CACNB4CACNA1ACACNA1GCACNG3CACNA1F
	SCHEMBL3716533	0.90	CACNB4 (0.54)	CACNB4CACNA1ACACNA1GCACNG3CACNA1F
	SCHEMBL3709887	0.89	GPR119 (0.48)	CACNB4CACNA1ACACNA1GCACNG3CACNA1F
	SCHEMBL3708948	0.89	GPR119 (0.51)	CACNB4CACNA1ACACNA1GCACNG3CACNA1F
	SCHEMBL3055131	0.88	GPR119 (0.47)	CACNB4CACNA1ACACNA1GCACNG3CACNA1F
	SCHEMBL3805418	0.86	KDM1A (0.53)	CACNB4CACNA1ACACNA1GCACNG3CACNA1F
	SCHEMBL3711289	0.86	HRH1 (0.52)	PDE4APDE4BPDE4CPDE4DHRH1
	SCHEMBL3715445	0.84	HRH1 (0.48)	GPR119PDE4APDE4BPDE4CPDE4D
	SCHEMBL3718500	0.84	HRH1 (0.52)	HRH1KCNH2
	SCHEMBL3648875	0.83	HRH1 (0.46)	GPR119HRH1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.