Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 18/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717204 | 0.93 | HRH4 (0.52) | HRH4HRH3CDK1CDK2 | |
| SCHEMBL3717198 | 0.93 | HRH4 (0.52) | HRH4HRH3CDK1CDK2 | |
| SCHEMBL1773838 | 0.77 | LMNA (0.51) | HRH3 | |
| SCHEMBL6510068 | 0.76 | HRH4 (0.55) | HRH4HRH3 | |
| SCHEMBL3207369 | 0.76 | HRH4 (0.57) | HRH4HRH3 | |
| SCHEMBL4420312 | 0.75 | HRH3 (0.57) | HRH4HRH3 | |
| SCHEMBL1990283 | 0.75 | HRH3 (0.48) | HRH4HRH3 | |
| SCHEMBL4419619 | 0.75 | HRH3 (0.41) | HRH4HRH3 | |
| SCHEMBL23931281 | 0.75 | PDPK1 (0.43) | HRH4HRH3 | |
| SCHEMBL3710451 | 0.75 | HRH4 (0.60) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094721-A1 | PIPERIDIN-PYRIMIDINE DERIVATIVES AS ANTAGONISTS OF HISTAMINE H4 RECEPTOR | PALAU PHARMA, S. A. (ES) | 2010-08-26 | — | — | WO | disclosed |