Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065283 | 0.88 | MYC (0.47) | MYCBCAT2KEAP1NFE2L2LMNA | |
| SCHEMBL370920 | 0.86 | MYC (0.54) | MYCCXCR5LMNACYP3A4MEN1 | |
| SCHEMBL4235369 | 0.85 | CXCR5 (0.49) | MYCCXCR5LMNACYP3A4MAPT | |
| SCHEMBL5478290 | 0.84 | PARP1 (0.45) | BCAT2KEAP1NFE2L2LMNACYP3A4 | |
| SCHEMBL5476512 | 0.83 | BCAT2 (0.59) | BCAT2KEAP1NFE2L2LMNACYP3A4 | |
| SCHEMBL5478916 | 0.82 | MEN1 (0.44) | BCAT2KEAP1NFE2L2MEN1KMT2A | |
| SCHEMBL2964481 | 0.82 | PARP1 (0.45) | BCAT2KEAP1NFE2L2LMNACYP3A4 | |
| SCHEMBL5482149 | 0.81 | MYC (0.47) | MYCBCAT2KEAP1NFE2L2MAPT | |
| SCHEMBL5482646 | 0.81 | PPARG (0.45) | BCAT2MAPTALDH1A1HPGDPPARG | |
| SCHEMBL5742619 | 0.80 | MYC (0.53) | MYCBCAT2KEAP1NFE2L2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |