Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.45 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.45 |
| ▸ | FBP1 | P09467 | 2/20 | 0.40 |
| ▸ | USP10 | Q14694 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | THRA | P10827 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710221 | 0.88 | FBP1 (0.47) | FBP1THRBTHRAPPARG | |
| SCHEMBL2822552 | 0.70 | CDC7 (0.68) | CDC7DBF4MAPTALDH1A1GAA | |
| SCHEMBL3712683 | 0.69 | CDC7 (0.48) | CDC7DBF4MEN1LMNAKMT2A | |
| SCHEMBL3710922 | 0.69 | CDC7 (0.52) | CDC7DBF4USP10MAPTTHRB | |
| SCHEMBL3710384 | 0.69 | CDC7 (0.48) | CDC7DBF4LMNAMAPTALDH1A1 | |
| SCHEMBL28459984 | 0.69 | FBP1 (0.73) | FBP1MEN1LMNAKMT2AMAPT | |
| SCHEMBL3708038 | 0.69 | CDC7 (0.48) | CDC7DBF4USP10MEN1LMNA | |
| SCHEMBL23794717 | 0.67 | CDC7 (0.67) | CDC7DBF4MEN1KMT2AMAPT | |
| SCHEMBL3714233 | 0.67 | XDH (0.54) | CDC7DBF4MEN1LMNAKMT2A | |
| SCHEMBL23794795 | 0.67 | CDC7 (0.79) | CDC7DBF4MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |