Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.31 |
| ▸ | HTR2B | P41595 | 4/20 | 0.31 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR1A | P08908 | 3/20 | 0.31 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3706111 | 0.77 | ACACB (0.33) | — | |
| Hydrochloric Acid SCHEMBL4685567 | 0.73 | TAAR1 (0.55) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL3706366 | 0.72 | ACACB (0.33) | — | |
| SCHEMBL7159772 | 0.69 | SLC6A2 (0.40) | SLC6A4SLC6A2SLC6A3HTR2CHTR2A | |
| SCHEMBL7160512 | 0.69 | SLC6A2 (0.40) | SLC6A4SLC6A2SLC6A3HTR2CHTR2A | |
| SCHEMBL7154930 | 0.69 | SLC6A2 (0.40) | SLC6A4SLC6A2SLC6A3HTR2CHTR2A | |
| SCHEMBL5018926 | 0.68 | CTNNB1 (0.43) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL11696742 | 0.68 | TAAR1 (0.55) | TAAR1SLC6A4SLC6A2SLC6A3HTR2C | |
| SCHEMBL8938407 | 0.68 | AKR1B1 (0.43) | GAAMAPT | |
| SCHEMBL30855405 | 0.67 | ALDH1A1 (0.40) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077976-A2 | PROKINETICIN RECEPTOR ANTAGONISTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-07-08 | — | — | WO | disclosed |