Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.32 |
| ▸ | WNT3A | P56704 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938407 | 0.73 | AKR1B1 (0.43) | CTNNB1WNT3ARAB9ANPC1POLB | |
| SCHEMBL3709470 | 0.72 | TAAR1 (0.36) | — | |
| SCHEMBL3706111 | 0.72 | ACACB (0.33) | ACACBP2RX3 | |
| SCHEMBL7133381 | 0.69 | TAAR1 (0.36) | ACACBNPSR1 | |
| SCHEMBL7362444 | 0.67 | DPP4 (0.39) | — | |
| SCHEMBL5018926 | 0.66 | CTNNB1 (0.43) | ACACBCTNNB1WNT3ARAB9ANPC1 | |
| SCHEMBL5707367 | 0.65 | KMT2A (0.48) | ACACBRAB9ANPC1 | |
| SCHEMBL9227299 | 0.65 | TRPA1 (0.47) | — | |
| SCHEMBL8938549 | 0.65 | AKR1B1 (0.44) | RAB9ANPC1POLB | |
| SCHEMBL18383090 | 0.65 | HPGD (0.51) | RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077976-A2 | PROKINETICIN RECEPTOR ANTAGONISTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-07-08 | — | — | WO | disclosed |