Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 4/20 | 0.51 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3398629 | 0.99 | PRMT1 (0.52) | PRMT1SCN10ASLC2A1ABCB1ACHE | |
| Trifluoroacetic Acid SCHEMBL3398116 | 0.95 | PRMT1 (0.47) | PRMT1SCN10ASLC2A1ABCB1ACHE | |
| SCHEMBL3713576 | 0.91 | SLC2A1 (0.42) | PRMT1SLC2A1PRMT6PIM1GRM2 | |
| Hydrochloric Acid SCHEMBL3398480 | 0.90 | SLC2A1 (0.41) | PRMT1SLC2A1PRMT6PIM1GRM2 | |
| SCHEMBL3712620 | 0.90 | SLC2A1 (0.41) | PRMT1SLC2A1PRMT6PIM1GRM2 | |
| Hydrochloric Acid SCHEMBL3394437 | 0.89 | SLC2A1 (0.40) | PRMT1SLC2A1PRMT6PIM1GRM2 | |
| Trifluoroacetic Acid SCHEMBL3398157 | 0.84 | SERPINE1 (0.40) | SLC2A1PRMT6GRM2ESR1 | |
| SCHEMBL3705658 | 0.83 | SLC2A1 (0.35) | PRMT1SCN10ASLC2A1PRMT6PIM1 | |
| SCHEMBL3707693 | 0.83 | PRMT6 (0.40) | SLC2A1ACHEPRMT6PIM1 | |
| SCHEMBL3391536 | 0.82 | PRMT6 (0.39) | PRMT1SLC2A1ACHEPRMT6GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081904-A1 | 4 ( 1H) -PYRIDINONE DERIVATIVES AND THEIR USE AS ANTIMALARIA AGENTS | GLAXO GROUP LIMITED (GB) | 2010-07-22 | — | — | WO | claimed |