Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 18/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3065325 | 0.99 | PIK3CA (0.46) | PIK3CAPRKAA2STAT3 | |
| Bromide SCHEMBL3053365 | 0.89 | PRKAA2 (0.47) | PIK3CAPRKAA2STAT3 | |
| Oxalic Acid SCHEMBL3060675 | 0.88 | PIK3CA (0.42) | PIK3CAPRKAA2STAT3 | |
| SCHEMBL3052158 | 0.86 | SMN1; SMN2 (0.46) | PIK3CAPRKAA2STAT3 | |
| SCHEMBL3052627 | 0.86 | LGALS8 (0.41) | STAT3 | |
| Bromide SCHEMBL3061338 | 0.85 | PIK3CA (0.45) | PIK3CAPRKAA2STAT3 | |
| SCHEMBL3055575 | 0.85 | HRH3 (0.41) | PIK3CASTAT3 | |
| Bromide SCHEMBL3068012 | 0.83 | PRKAA2 (0.46) | PIK3CAPRKAA2STAT3 | |
| Bromide SCHEMBL3067536 | 0.83 | FAAH (0.44) | PIK3CAPRKAA2STAT3 | |
| Bromide SCHEMBL3051472 | 0.83 | STAT3 (0.55) | PIK3CAPRKAA2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207773-B1 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMA CO LTD (JP) | 2012-07-11 | — | — | EP | disclosed |
| EP-2207773-A2 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | Otsuka Pharmaceutical Co., Ltd. (JP) | 2010-07-21 | — | — | EP | disclosed |
| WO-2009057811-A2 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-05-07 | — | — | WO | disclosed |