Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | CTSG | P08311 | 2/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.40 |
| ▸ | CMA1 | P23946 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1871593 | 0.78 | TSHR (0.54) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 | |
| Hippuric Acid SCHEMBL3710131 | 0.78 | KDM4E (0.44) | SMN1; SMN2RAB9ANPC1GAAMAPT | |
| Gluconic Acid SCHEMBL28056864 | 0.72 | PDE4A (0.44) | SMN1; SMN2RAB9ANPC1GAAMAPT | |
| SCHEMBL14219258 | 0.72 | GPR139 (0.55) | SMN1; SMN2PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL5655365 | 0.70 | PRSS1 (0.68) | SMN1; SMN2PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL8526433 | 0.69 | PPARG (0.38) | GAAHPGD | |
| SCHEMBL14219779 | 0.69 | GPR139 (0.51) | SMN1; SMN2PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL21195781 | 0.69 | SLC1A1 (0.49) | KMT2AMEN1 | |
| SCHEMBL6057627 | 0.69 | HPGD (0.43) | SMN1; SMN2GAAKMT2AMEN1MAPT | |
| SCHEMBL18045621 | 0.69 | TSHR (0.45) | SMN1; SMN2RAB9ANPC1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086366-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2010-08-05 | — | — | WO | disclosed |