Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.50 |
| ▸ | CTSG | P08311 | 2/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | CMA1 | P23946 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219779 | 0.86 | GPR139 (0.51) | GPR139NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL3961994 | 0.82 | GAA (0.59) | GPR139TSHRNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9331679 | 0.81 | GAA (0.57) | GPR139TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5655365 | 0.80 | PRSS1 (0.68) | GPR139NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL9135411 | 0.80 | GPR139 (0.51) | GPR139NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL30539770 | 0.79 | GAA (0.59) | GPR139NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL29117026 | 0.78 | PRSS1 (0.49) | GPR139NPC1RAB9AGAAKMT2A | |
| SCHEMBL11519981 | 0.78 | GAA (0.53) | GPR139NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL1221369 | 0.78 | RAB9A (0.66) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6084716 | 0.78 | PTPRC (0.62) | GPR139NPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101095648-A | Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds | OREAL (FR) | 2008-01-02 | — | — | CN | claimed |
| EP-1911438-A2 | Cosmetic composition containing a derivative of dibenzoylmethane and a arylalkyl amide or ester compound; method of photostabilising the derivative of dibenzoylmethane | L'Oréal (FR) | 2008-04-16 | — | — | EP | disclosed |
| US-20080019930-A1 | Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds | L'OREAL (FR) | 2008-01-24 | — | — | US | disclosed |
| US-20080019930-A1 | Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds | L'OREAL (FR) | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080019930-A1 | Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds | TYR, DDT, AADAC | GPR139 4096/4885TSHR 4288/4885NPC1 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.