Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | HTR1D | P28221 | 1/20 | 0.58 |
| ▸ | HTR1B | P28222 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RBP4 | P02753 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3714314 | 0.92 | TRPV1 (0.60) | SMN1; SMN2ALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL3707073 | 0.87 | MAPT (0.52) | SMN1; SMN2ALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL3716149 | 0.86 | POLB (0.75) | SMN1; SMN2MEN1KMT2ATRPV1HTR1A | |
| SCHEMBL3713332 | 0.86 | MEN1 (0.59) | SMN1; SMN2ALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL13234941 | 0.85 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL3709422 | 0.85 | LMNA (0.53) | SMN1; SMN2ALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL3716167 | 0.84 | TRPV1 (0.75) | MEN1KMT2ATRPV1RBP4 | |
| SCHEMBL3710357 | 0.83 | TRPV1 (0.74) | TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL3781732 | 0.83 | CA12 (0.71) | SMN1; SMN2ALDH1A1MEN1KMT2ATRPV1 | |
| SCHEMBL13234916 | 0.82 | MAPT (0.70) | SMN1; SMN2ALDH1A1NPSR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010092342-A1 | ORGANOSILICON COMPOUNDS AND THEIR USE AS THE MODULATORS OF THE TRPV1 RECEPTOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-19 | — | — | WO | disclosed |