Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 17/20 | 0.60 |
| ▸ | THRA | P10827 | 16/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710103 | 0.88 | THRB (0.50) | THRBTHRAEPHX1EPHX2 | |
| SCHEMBL3780490 | 0.88 | THRB (0.45) | THRBTHRAEPHX1EPHX2 | |
| SCHEMBL3706172 | 0.87 | THRB (0.58) | THRBTHRAEPHX1EPHX2 | |
| SCHEMBL3778662 | 0.85 | THRB (0.63) | THRBTHRAEPHX1EPHX2 | |
| SCHEMBL3702776 | 0.85 | THRB (0.58) | THRBTHRA | |
| SCHEMBL3226122 | 0.82 | THRB (0.60) | THRBTHRAEPHX1EPHX2 | |
| SCHEMBL3219162 | 0.82 | THRB (0.60) | THRBTHRAEPHX1EPHX2 | |
| SCHEMBL3778658 | 0.81 | THRB (0.67) | THRBTHRAEPHX1EPHX2 | |
| SCHEMBL3807063 | 0.81 | THRB (0.58) | THRBTHRAEPHX1EPHX2 | |
| SCHEMBL3702844 | 0.79 | THRB (0.58) | THRBTHRAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | claimed |