Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 4/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3704850 | 0.93 | GPBAR1 (0.34) | PPARDCYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2342592 | 0.92 | LPAR1 (0.39) | PPARDCYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3711309 | 0.88 | FTO (0.36) | GPBAR1ALDH1A1HPGDTSHR | |
| SCHEMBL3708660 | 0.88 | LPAR1 (0.40) | PPARDENPP2LPAR1LPAR2LPAR3 | |
| SCHEMBL3707177 | 0.88 | LPAR1 (0.34) | PPARDLPAR1LPAR2LPAR3ALDH1A1 | |
| SCHEMBL3714465 | 0.87 | LPAR1 (0.45) | PPARDENPP2LPAR1LPAR2LPAR3 | |
| SCHEMBL3712288 | 0.87 | PPARD (0.39) | PPARDLPAR1LPAR2LPAR3 | |
| SCHEMBL3709239 | 0.86 | PPARD (0.46) | PPARDLPAR1LPAR2LPAR3MAPT | |
| SCHEMBL3707320 | 0.85 | CTSA (0.38) | PPARDLPAR1LPAR2LPAR3 | |
| SCHEMBL3709682 | 0.85 | FTO (0.39) | SLC6A2SLC6A4SLC6A3GPBAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | claimed |
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |