Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711037 | 0.93 | PTGER1 (0.39) | GPBAR1MAPTLMNACYP2D6SLC6A2 | |
| SCHEMBL3707844 | 0.88 | L3MBTL1 (0.38) | MAPTLMNAHTTCYP1A2CYP2C9 | |
| SCHEMBL3717656 | 0.88 | KMT2A (0.34) | MAPTNPSR1TSHRHTTSLC26A6 | |
| SCHEMBL3709586 | 0.87 | LPAR1 (0.38) | HTTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL3713874 | 0.87 | L3MBTL1 (0.37) | GPBAR1MAPTTSHRHTTNPC1 | |
| SCHEMBL3713473 | 0.86 | PPARD (0.39) | GPBAR1MAPTLMNAHTTNPC1 | |
| SCHEMBL3711309 | 0.86 | FTO (0.36) | GPBAR1TSHRTDP1ALDH1A1HPGD | |
| SCHEMBL2342592 | 0.85 | LPAR1 (0.39) | GPBAR1MAPTCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL3706374 | 0.85 | MDM2 (0.39) | HTTNPC1RAB9APPARD | |
| SCHEMBL3709682 | 0.85 | FTO (0.39) | GPBAR1MAPTLMNASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |