Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ACR | P10323 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335629 | 0.92 | SLC6A3 (0.44) | FTOALDH1A1HPGDACRSLC6A4 | |
| SCHEMBL3711309 | 0.91 | FTO (0.36) | FTOALDH1A1HPGDACRKDM4E | |
| SCHEMBL3714395 | 0.88 | NR1H4 (0.40) | FTOALDH1A1HPGDACRSMN1; SMN2 | |
| SCHEMBL3710274 | 0.85 | JMJD6 (0.38) | FTOKDM4ENPSR1MAPTLMNA | |
| SCHEMBL3711037 | 0.85 | PTGER1 (0.39) | ALDH1A1HPGDSLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3704850 | 0.85 | GPBAR1 (0.34) | ALDH1A1HPGDSLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3702769 | 0.84 | S1PR1 (0.38) | FTOALDH1A1HPGDACRSMN1; SMN2 | |
| SCHEMBL3711407 | 0.84 | ACR (0.36) | FTOALDH1A1HPGDACRKDM4E | |
| SCHEMBL2336114 | 0.83 | LTB4R2 (0.37) | FTOALDH1A1HPGDACRKDM4E | |
| SCHEMBL3710286 | 0.83 | MAPT (0.40) | FTOALDH1A1HPGDACRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |