Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | CLK1 | P49759 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3950463 | 0.80 | EGFR (0.60) | EGFRALDH1A1CHEK1CYP2C19GUSB | |
| SCHEMBL7888746 | 0.80 | RAB9A (0.53) | EGFRRAB9AGAANPC1CLK1 | |
| SCHEMBL30443128 | 0.80 | ACR (0.48) | RAB9ANPC1MAPTPOLBALDH1A1 | |
| SCHEMBL3705300 | 0.80 | RAB9A (0.50) | EGFRRAB9AGAANPC1CLK1 | |
| SCHEMBL3702956 | 0.79 | CDC7 (0.59) | MAPTALDH1A1CCNCCDK8MEN1 | |
| SCHEMBL725782 | 0.79 | MAOA (0.53) | EGFRRAB9AGAANPC1MAPT | |
| SCHEMBL27108838 | 0.79 | RAB9A (0.72) | RAB9AGAANPC1CLK1MAPT | |
| SCHEMBL12582252 | 0.79 | RAB9A (0.72) | RAB9AGAANPC1CLK1MAPT | |
| SCHEMBL3711151 | 0.78 | CDC7 (0.59) | EGFRCCNCCDK8MAOAMMP2 | |
| SCHEMBL18002724 | 0.78 | RAB9A (0.61) | RAB9AGAANPC1CLK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |