Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29453958 | 0.92 | DNM1 (0.54) | DNM1FAAHMEN1KMT2A | |
| SCHEMBL9754663 | 0.80 | FAAH (0.51) | DNM1EPHX2FAAHMAPTBLM | |
| SCHEMBL9754668 | 0.79 | DNM1 (0.48) | DNM1EPHX2FAAHMAPTBLM | |
| SCHEMBL51584 | 0.77 | CNR1 (0.47) | FAAHCNR1ALDH1A1HPGDMAPT | |
| SCHEMBL29614882 | 0.77 | CNR1 (0.47) | FAAHCNR1ALDH1A1HPGDMAPT | |
| SCHEMBL8500918 | 0.77 | EPHX2 (0.44) | DNM1EPHX2CNR1CNR2TRPV1 | |
| SCHEMBL4864824 | 0.77 | TERT (0.63) | FAAHMAPTBLMMEN1KMT2A | |
| SCHEMBL4864817 | 0.77 | TERT (0.63) | FAAHMAPTBLMMEN1KMT2A | |
| SCHEMBL9251779 | 0.76 | KDM4E (0.44) | DNM1FAAHALDH1A1 | |
| SCHEMBL25134837 | 0.75 | DNM1 (0.82) | DNM1EPHX2CNR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231190-A1 | PARTICULATE DRUG CARRIERS AS DESENSITIZING AGENTS | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009072136-A1 | PARTICULATE DRUG CARRIERS AS DESENSITIZING AGENTS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2009-06-11 | — | — | WO | disclosed |