Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | AKT2 | P31751 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | BRD2 | P25440 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5182269 | 0.79 | MEN1 (0.50) | L3MBTL1ALOX5MAPTKMT2ANPC1 | |
| SCHEMBL12496375 | 0.77 | ADORA2A (0.52) | L3MBTL1SMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL13903600 | 0.77 | HSP90AA1 (0.49) | L3MBTL1ALOX5SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL21300216 | 0.75 | ADRA2A (0.42) | ALOX5AKT2BRD4CHEK1BRD2 | |
| SCHEMBL10205902 | 0.74 | L3MBTL1 (0.54) | L3MBTL1AKT2BRD4CHEK1BRD2 | |
| SCHEMBL31504610 | 0.74 | L3MBTL1 (0.54) | L3MBTL1AKT2BRD4CHEK1BRD2 | |
| Hydroquinone SCHEMBL1286582 | 0.74 | MEN1 (0.60) | L3MBTL1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3715112 | 0.73 | L3MBTL1 (0.52) | L3MBTL1AKT2BRD4CHEK1BRD2 | |
| SCHEMBL13869973 | 0.73 | ALDH1A1 (0.44) | SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL20792796 | 0.71 | PDE4A (0.48) | ALOX5PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119735554-A | Seed coating agent containing phenylpyrimidine compound and capable of promoting germination rate and seedling rate of seeds and application of seed coating agent | 江苏里下河地区农业科学研究所 | 2025-04-01 | — | — | CN | disclosed |
| US-20130310362-A1 | FUSED PYRIMIDINES | BAYER PHARMA AKTIEGESELLSCHAFT (DE) | 2013-11-21 | — | — | US | disclosed |
| EP-2396331-B1 | FUSED PYRIMIDINES AS AKT INHIBITORS | BAYER IP GMBH (DE) | 2013-10-16 | — | — | EP | disclosed |
| EP-2396331-A1 | FUSED PYRIMIDINES AS AKT INHIBITORS | Bayer Pharma Aktiengesellschaft (DE) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010091824-A1 | FUSED PYRIMIDINES AS AKT INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130310362-A1 | FUSED PYRIMIDINES | PIK3CA, MTOR, PIK3CD | L3MBTL1 3795/4885ALOX5 2802/4885AKT2 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.