Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 9/20 | 0.43 |
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712056 | 1.00 | HPGD (0.45) | HPGDKMT2AMEN1POLBRAB9A | |
| SCHEMBL12581928 | 0.84 | ALDH1A1 (0.41) | KMT2AMEN1POLBRAB9ANPC1 | |
| SCHEMBL31300805 | 0.83 | MEN1 (0.39) | HPGDKMT2AMEN1POLBRAB9A | |
| SCHEMBL23799825 | 0.83 | MEN1 (0.39) | HPGDKMT2AMEN1POLBRAB9A | |
| SCHEMBL23799823 | 0.83 | MEN1 (0.39) | HPGDKMT2AMEN1POLBRAB9A | |
| SCHEMBL14651323 | 0.82 | SMN1; SMN2 (0.41) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8328486 | 0.81 | PDK1 (0.43) | HPGDKMT2AMEN1POLBRAB9A | |
| SCHEMBL18512240 | 0.80 | TDP1 (0.48) | KMT2AMEN1POLBRAB9ANPC1 | |
| SCHEMBL14504048 | 0.79 | SIGMAR1 (0.47) | HPGDKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL17046623 | 0.77 | MEN1 (0.52) | HPGDKMT2AMEN1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |