SCHEMBL3712192

SCHEMBL3712192

Cn1nc(C(F)(F)F)cc1C(=O)CC(=O)C1CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
CYP3A4 P08684 1/20 0.44
HSD17B10 Q99714 1/20 0.44
POLB P06746 2/20 0.41
KCNT1 Q5JUK3 4/20 0.41
TRPV1 Q8NER1 1/20 0.40
KDM4E B2RXH2 2/20 0.40
CTSK P43235 1/20 0.40
GRN P28799 1/20 0.40
SORT1 Q99523 1/20 0.40
KDR P35968 1/20 0.40
CTSL P07711 1/20 0.40
VNN1 O95497 1/20 0.39
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19902317 0.81 ALDH1A1 (0.50) ALDH1A1CYP3A4HSD17B10POLBKCNT1
SCHEMBL13064210 0.73 KDM4E (0.51) ALDH1A1CYP3A4HSD17B10POLBKCNT1
SCHEMBL17920 0.73 GRN (0.71) ALDH1A1CYP3A4HSD17B10POLBKCNT1
SCHEMBL19994223 0.72 KDM4E (0.47) ALDH1A1CYP3A4HSD17B10POLBKCNT1
Hydrochloric Acid SCHEMBL8932269 0.71 GRN (0.69) ALDH1A1CYP3A4HSD17B10POLBKCNT1
SCHEMBL951323 0.71 KDM4E (0.50) ALDH1A1CYP3A4HSD17B10POLBKCNT1
SCHEMBL17732 0.71 KDM4E (0.50) ALDH1A1CYP3A4HSD17B10POLBKCNT1
SCHEMBL13020360 0.70 KDM4E (0.53) ALDH1A1CYP3A4HSD17B10POLBKCNT1
SCHEMBL30305711 0.70 KDM4E (0.49) ALDH1A1CYP3A4HSD17B10POLBKCNT1
SCHEMBL17452578 0.69 KDM4E (0.47) ALDH1A1CYP3A4HSD17B10POLBKCNT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010087294-A1 TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PROCESS FOR PRODUCING THE SAME AND PESTICIDE CONTAINING THE SAME ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-08-05 WO disclosed