Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | IDH1 | O75874 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076515 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10KMT2ATDP1 | |
| SCHEMBL3719538 | 0.82 | IDH1 (0.50) | KDM4EALDH1A1HSD17B10IDH1 | |
| SCHEMBL3714361 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10IDH1KMT2A | |
| SCHEMBL3708482 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10IDH1KMT2A | |
| SCHEMBL3709499 | 0.78 | IDH1 (0.49) | KDM4EALDH1A1HSD17B10IDH1KMT2A | |
| SCHEMBL15752905 | 0.78 | PDCD1 (0.45) | KDM4EALDH1A1TDP1HPGDALK | |
| SCHEMBL30088492 | 0.78 | PDCD1 (0.45) | KDM4EALDH1A1TDP1HPGDALK | |
| SCHEMBL12301250 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1HSD17B10KMT2ATDP1 | |
| SCHEMBL1420627 | 0.77 | ALOX15 (0.43) | KDM4EALDH1A1HSD17B10KMT2ALMNA | |
| SCHEMBL1420412 | 0.76 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393806-A1 | INHIBITORS OF JUN N-TERMINAL KINASE | Elan Pharmaceuticals Inc. (US) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010091310-A1 | INHIBITORS OF JUN N-TERMINAL KINASE | ELAN PHARMACEUTICALS, INC. (US) | 2010-08-12 | — | — | WO | disclosed |