Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 13/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | OXTR | P30559 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705108 | 0.85 | SLC6A9 (0.38) | SLC6A9SLC6A5L3MBTL1HPGD | |
| SCHEMBL3711687 | 0.84 | SLC6A9 (0.43) | SLC6A9SLC6A5OXTR | |
| SCHEMBL3709702 | 0.83 | SLC6A9 (0.41) | SLC6A9SLC6A5 | |
| SCHEMBL7894823 | 0.82 | — | — | |
| SCHEMBL7894825 | 0.82 | — | — | |
| SCHEMBL3707977 | 0.82 | — | — | |
| SCHEMBL7899357 | 0.74 | MAPT (0.43) | SLC6A9SLC6A5OXTR | |
| SCHEMBL7895248 | 0.73 | SCN9A (0.34) | SLC6A9L3MBTL1 | |
| SCHEMBL3711967 | 0.68 | OPRD1 (0.32) | SLC6A9SLC6A5OXTR | |
| SCHEMBL7894548 | 0.68 | OPRD1 (0.32) | SLC6A9SLC6A5OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087761-A1 | 2-AZA-BICYCLO[2.2.2]OCTANE COMPOUNDS AND USES THEREOF | ASTRAZENECA AB (SE) | 2010-08-05 | — | — | WO | disclosed |