Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL759434 | 0.87 | GPR119 (0.66) | GPR119 | |
| SCHEMBL2720772 | 0.84 | GPR119 (0.49) | GPR119 | |
| SCHEMBL2719913 | 0.83 | GPR119 (0.40) | GPR119 | |
| SCHEMBL2719977 | 0.79 | GPR119 (0.59) | GPR119 | |
| SCHEMBL288068 | 0.78 | GPR119 (0.47) | GPR119 | |
| SCHEMBL299959 | 0.76 | GPR119 (0.80) | GPR119 | |
| SCHEMBL17091616 | 0.76 | GPR119 (0.60) | GPR119 | |
| SCHEMBL288936 | 0.76 | GPR119 (0.57) | GPR119 | |
| SCHEMBL17091636 | 0.75 | GPR119 (0.67) | GPR119 | |
| SCHEMBL17091630 | 0.74 | GPR119 (0.64) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128425-A1 | GPR 119 MODULATORS | PFIZER INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010128414-A1 | GPR 119 MODULATORS | PFIZER INC. (US) | 2010-11-11 | — | — | WO | disclosed |