Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 14/20 | 0.35 |
| ▸ | FEN1 | P39748 | 14/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ARF6 | P62330 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717418 | 0.88 | DGAT1 (0.39) | SLC2A1DGAT1ALOX5APFEN1 | |
| SCHEMBL13049075 | 0.82 | FEN1 (0.40) | DGAT1ALOX5APFEN1 | |
| SCHEMBL13049103 | 0.82 | SCN10A (0.37) | SLC2A1DGAT1AR | |
| SCHEMBL4485644 | 0.80 | FEN1 (0.44) | SLC2A1DGAT1ALOX5APFEN1 | |
| SCHEMBL3718803 | 0.73 | AR (0.39) | SLC2A1AR | |
| SCHEMBL4486314 | 0.73 | SLC2A1 (0.43) | SLC2A1DGAT1ALOX5APFEN1ALDH1A1 | |
| SCHEMBL4491220 | 0.72 | SLC2A1 (0.43) | SLC2A1DGAT1ALOX5APFEN1ARF6 | |
| SCHEMBL4472769 | 0.70 | KDM1A (0.45) | SLC2A1ALOX5APFEN1MEN1KMT2A | |
| SCHEMBL3713645 | 0.69 | MEN1 (0.33) | MEN1ALDH1A1KMT2AAR | |
| SCHEMBL3723682 | 0.69 | DGAT1 (0.37) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142741-A1 | PHENYLPYRIDYLPYRIDONES FOR USE AS ANTIMALARIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010142741-A1 | PHENYLPYRIDYLPYRIDONES FOR USE AS ANTIMALARIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |