Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717421 | 0.88 | HSD11B1 (0.34) | HSD11B1CTSA | |
| SCHEMBL3713643 | 0.69 | SLC2A1 (0.39) | MEN1ALDH1A1KMT2AAR | |
| SCHEMBL18784923 | 0.61 | ALOX5AP (0.44) | AR | |
| SCHEMBL21778738 | 0.57 | FEN1 (0.50) | — | |
| SCHEMBL14729682 | 0.57 | RXRA (0.47) | PTGER1 | |
| SCHEMBL206609 | 0.55 | TSHR (0.68) | ALDH1A1ELANE | |
| SCHEMBL27831115 | 0.55 | IDO1 (0.54) | MEN1KMT2A | |
| SCHEMBL12769594 | 0.54 | ELANE (0.53) | ALDH1A1ELANE | |
| SCHEMBL9449212 | 0.54 | IDO1 (0.49) | KMT2APPARG | |
| SCHEMBL24986392 | 0.54 | ALDH1A1 (0.46) | ALDH1A1KMT2AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142741-A1 | PHENYLPYRIDYLPYRIDONES FOR USE AS ANTIMALARIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |